Maliha Tasnim

Research Description: Determine the genome-wide occupancy and gene regulation patterns for Tbx2a, Tbx2b, and Tbx3 to determine the level of functional divergence between these proteins (downstream targets), to examine how amino-acid substitutions we have identified in Tbx2a and Tbx2b affect their protein-protein interactions (binding partners) and to classify 161 gene pairs we have shown have similar temporal expression patterns in the embryonic zebrafish heart as having divergent or conserved spatial expression patterns in the embryo.