Publications

Siegmann MJ, Zachs DP, Kenny JD, Lark ARS, Mir FA, Melonakos ED, Hozan M, Kaufmann ST, Goldblum RR, Liu Y, Nolan MA, Cohen G, Choi J, White CG, Crowley EA, Carpenter AH, Toro BA, Syme CE, Brown EN, Nehs CJ (2026) Neurophysiological Differences Between Dexmedetomidine Sedation and Natural Sleep Across the Rodent Lifespan: Implications for Aging and Perioperative Brain Health. Anesthesiology and Perioperative Science.

Melonakos ED, Siegmann MJ, *Rey C, *O’Brien C, Nikolaeva KK, Solt K, Nehs CJ (2021) Excitation of Putative Glutamatergic Neurons in the Rat Parabrachial Nucleus Region Reduces Delta Power during Dexmedetomidine but not Ketamine Anesthesia. Anesthesiology 135: 633–648. doi:10.1097/ALN.0000000000003883

Kato R, Zhang ER, Mallari OG, Moody OA, Vincent KF, Melonakos ED, Siegmann MJ, Nehs CJ, Houle TT, Akeju O, Solt K. 2021. D-Amphetamine rapidly reverses dexmedetomidine-induced unconsciousness in rats. Front Pharmacol. 12:668285. doi: 10.3389/fphar.2021.668285. PMID: 34084141.

Melonakos ED, Siegmann MJ, Rey C, O'Brien C, Nikolaeva KK, Solt K, Nehs CJ. 2021. Excitation of putative glutamatergic neurons in the rat parabrachial nucleus region reduces delta power during dexmedetomidine but not ketamine anesthesia. Anesthesiology. 135(4):633-648. doi: 10.1097/ALN.0000000000003883. PMID: 34270686.

Moody OA, Zhang ER, Vincent KF, Kato R, Melonakos ED, Nehs CJ, Solt K. 2021. The neural circuits underlying general anesthesia and sleep. Anesth Analg. 132(5):1254-1264. doi: 10.1213/ANE.0000000000005361. PMID: 33857967. Review.

Melonakos ED, Moody OA, Nikolaeva K, Kato R, Nehs CJ, Solt K. 2020. Manipulating neural circuits in anesthesia research. Anesthesiology. 133(1):19-30. doi: 10.1097/ALN.0000000000003279. PMID: 32349073. Review.

Melonakos ED, White JA, Fernandez FR. 2019. A model of cholinergic suppression of hippocampal ripples through disruption of balanced excitation/inhibition. Hippocampus. 29(9):773-786. doi: 10.1002/hipo.23051. PMID: 30417958.

Ohtani T, Nestor PG, Bouix S, Newell D, Melonakos ED, McCarley RW, Shenton ME, Kubicki M. 2017. Exploring the neural substrates of attentional control and human intelligence: Diffusion tensor imaging of prefrontal white matter tractography in healthy cognition. Neuroscience. 341:52-60. doi: 10.1016/j.neuroscience.2016.11.002. PMID: 27840231.

Melonakos ED, White JA, Fernandez FR. 2016. Gain modulation of cholinergic neurons in the medial septum-diagonal band of Broca through hyperpolarization. Hippocampus. 26(12):1525-1541. doi: 10.1002/hipo.22653. PMID: 27588894.

Ohtani T, Bouix S, Lyall AE, Hosokawa T, Saito Y, Melonakos E, Westin CF, Seidman LJ, Goldstein J, Mesholam-Gately R, Petryshen T, Wojcik J, Kubicki M. 2015. Abnormal white matter connections between medial frontal regions predict symptoms in patients with first episode schizophrenia. Cortex. 71:264-76. doi: 10.1016/j.cortex.2015.05.028. PMID: 26277547.

Ohtani T, Bouix S, Hosokawa T, Saito Y, Eckbo R, Ballinger T, Rausch A, Melonakos E, Kubicki M. 2014. Abnormalities in white matter connections between orbitofrontal cortex and anterior cingulate cortex and their associations with negative symptoms in schizophrenia: a DTI study. Schizophr Res. 157(1-3):190-7. doi: 10.1016/j.schres.2014.05.016. PMID: 24962436.

Nelson SC, Neeley SK, Melonakos ED, Bell JD, Busath DD. 2012. Fluorescence anisotropy of diphenylhexatriene and its cationic Trimethylamino derivative in liquid dipalmitoylphosphatidylcholine liposomes: opposing responses to isoflurane. BMC Biophys. 5:5. doi: 10.1186/2046-1682-5-5. PMID: 22444827.

Melonakos ED, Shenton ME, Rathi Y, Terry DP, Bouix S, Kubicki M. 2011. Voxel-based morphometry (VBM) studies in schizophrenia-can white matter changes be reliably detected with VBM? Psychiatry Res. 193(2):65-70. doi: 10.1016/j.psychresns.2011.01.009. PMID: 21684124.