Publications

Cannon M., Peldyak J., and Reynolds P.R. 2026. Micro/nanoplastics and periodontitis: An environmental microbiology perspective on oral retention and systemic risk. Microorganisms, 2026, 13, x.

Elggren CW, Iverson CH, Morris MD, Cooper-Leavitt EF, Parker G, Richardson AW, Reynolds AP, Cortes PM, Bikman BT, and Reynolds PR. 2026. Testosterone Replacement Therapy in Women Is Associated with Improved Symptom Burden and Favorable Biomarker Changes: A Retrospective Observational Study. JPM, 2026, 16, 231.

Morris TJ, Morris MD, Parker AJ, Heggie JR, Roeth EJ, Parker G, Beus MK, Ricks R, Shafer LT, Poulos TS, Nevers DS, D'Agostino DP, Arroyo JA, Parrish RR, Reynolds PR, and Bikman BT. 2026. Disparate Hepatic Mitochondrial and Inflammatory Effects of Ketone Supplements. Nutrients, 2026, 18, 675.

Hiatt L., Davidson B.D., Beck L., Sturgis K., Evans E., Thurmond E., Boyer M., Bikman B.T., Reynolds P.R., and Arroyo J.A. 2026. Maternal lung inflammation and apoptosis following gestational exposure to secondhand smoke and e-cigaratte vapor: implications formaternal-fetal health. Exp Mol Path, 145 (2026): 105026.

Sturgis K.A., Davidson B.D., Richardson A.W., Hyatt O., Edwards B.C., Evans E.P., Campbell C., Radford J.H., Arroyo J.A., Bikman B.T., and Reynolds P.R. 2025. Potential use of Vyn202, a novel small molecular bromodomain and end-terminal inhibitor, in mitigating secondhand smoke (SHS)-induced pulmonary inflammation. Curr. Issues Mol. Biol., 2025,47, 1062.

Roeth E., Morris M., Reynolds A.R., Reynolds E.M., Hungerford R., Livingston E.J., Richardson A.W., Bikman B.T., and Reynolds P.R. 2025. Personalized Supplementation is Associated with Reduced Inflammatory Biomarkers: A 12-Week Observational Study. MDPI Life, 2025, 15, 1887.

Roeth E.J., Parker G., Cooper-Leavitt E.F., Beus C.G., Braithwaite C.R., Morris M.D., Reynolds P.R., Evans E.P., Radford J.H., Davis F.D., Reynolds P.R., Parrish R.R., and Bikman B.T. 2025. Effect of exogenous ketones as an adjunct to low-calorie diet on metabolic markers. Nutrients, 2025, 17, 3582.

Chou A., Frank E., Reall M., Hiatt O., Beck L., Reynolds P.R., Pickett B.E., and Arroyo J.A. 2025. Secondhand smoke exposure timing triggers distinct placental responses in mouse pregnancy. Cells, 14, 1735.

Hirst G., Ross Z., Rose A., Graff N., Campbell K., Reynolds P.R., and Terry B. 2025. Quantifying layer-specific thickness in porcine large intestine using x-ray microscopy. Microscopy, 2025, 00:1-7 doi: 10.1093/jmicro/dfaf041.

Chou A., Hiatt O., Davidson B., Reynolds P.R., Pickett B.E., and Arroyo J.A. 2025. Vaping in pregnancy: Unraveling Molecular Drivers of Preeclampsia and Fetal Growth Restriction. Int. J. Med. Sci. 2025, 26, 10009.

Ponder L., Kinney R., Chatterjee A., Vu K., Sidhu H., Patel N., Desai T., Orr III D.L., Arroyo J.A., and Reynolds P.R. 2025. Inflammatory molecule elaboration in secondhand smoke (SHS) or conditional RAGE transgenic modeling of chronic rhinosinusitis (CRS). Curr Issues Mol. Biol 2025, 47, 740.

Chou A., Davidson B., Reynolds P.R., Pickett B.E., and Arroyo J.A. 2025. Reversing preeclampsia pathology: AXL inhibition restores mitochondrial function and ECM balance. Cells., 14, 1229.

Kinney R., Ponder L., Patel N., Chatterjee A., Vu K., Sidhu H., Bikman B.T., Reynolds P.R. and Arroyo J.A. 2025. Comparative effects of cigarette smoke and e-cigarette vapor on oral squamous cell carcinoma: unraveling distinct molecular pathways. Dent Res Oral Health, 8:97-103.

Palmer I.L., Parker G., Chiu A.T., Beus C.G., Evans E.P., Radford J.H., Braithwaite C.R., Van Slooten R.D., Cooper-Leavitt E.T., Moore Z.E., Clarke D.M., Parrish R., Arroyo J.A., Reynolds P.R., and Bikman B.T. 2025. RAGE knockout mitigates diet-induced obesity and metabolic disruption. Metabolites, 15,524.

Beck L., Kirkham M.N., Shin M., Bikman B.T., Reynolds P.R., and Arroyo J.A. 2025. Impact of secondhand smoke and e-cigarette exposure on placental apoptotic and growth-regulatory proteins in mouse pregnancy. Cells, 14, 453.

Broberg E., English J., Clarke D.M., Shin M.J., Bikman B.T., Reynolds P.R., and Arroyo J.A. 2024. Impact of gestational diabetes treatment modalities on placental metabolic adaptions: differential roles of PKM2, AMPK, and mTOR pathways. Cells, 14, 416.

Redford J.H., Evans E.P., Edwards I.T., Arroyo J.A., Bikman B.T., and Reynolds P.R. 2025. Diesel particulate matter (DPM)-induced metabolic disruption is mitigated by sodium copper chlorophyllin. Nutrients, 17, 717.

Jackson M., Gibson T.M., Frank E., Hill G., Davidson B., Reynolds P.R., Bikman B.T., Pickett B.E., and Arroyo J.A. 2025. Transcriptomic insights into Gas-6-induced placental dysfunction: gene targets for preeclamsia therapy. Cells, 14, 278.

Cooper-Leavitt-Cooper E.T., Shin M.J., Beus C.G., Chiu A.T., Parker G., Radford J.H., Evans E.P., Edwards I.T., Arroyo J.A., Reynolds P.R., and Bikman B.T. 2025. The incretin effect of Yerbe Mate (Ilex paragauariensis) is partially dependent on gut-mediated metabolism of ferulic acid. Nutrients 2025, 17(4), 625.

Clarke D.M., Kirkham M.N., Beck L.B., Campbell C., Alcorn H., Bikman B.T., Arroyo J.A., and Reynolds P.R. 2024. Temporal RAGE over-expression disrupts lung development by modulating apoptotic signaling. Curr. Issues Mol. Biol., 2024, 46, 14453-14463.

Remund NP, Larsen JG, Shin MJ, Warren CE, Palmer IL, Kim IJ, Cooper-Leavitt ET, Clarke DM, Beus CG, Johnson RJ, Arroyo JA, Reynolds PR, and Bikman BT. 2024. The role of betahydroxybuterate in mitigating the inflammatory and metabolic consequences of uric acid. Metabolites, 14, 679.

Clarke DM, Koutnik AP, Johnson RJ, DeBlasi JM, Bikman BT, Arroyo JA, and Reynolds PR. 2024. Differential rates of glycation following exposure to unique monosaccharides. Int. J. Med. Sci. 2024, 25, 6921.

Curtis KL, Chang A, Johnston JD, Beard JD, Collingwood SC, LeCheminant JD, Peterson NE, South AJ, Farnsworth CB, Sanjel S, Bikman BT, Arroyo JA, and Reynolds PR. 2024. Differential inflammatory cytokine elaboration in serum from brick kiln workers in Bhaktapur, Nepal. Diseases 2024, 12,129.

Clarke D, Yeates E, Davis G, Harward K, Robertson P, Licari FW, Winden DR, Reynolds PR, and Arroyo JA. 2024. RAGE expression and invasiveness of oral squamous cell carcinoma cells via differential expression of matrix remodeling enzymes. J Oral Dent Health, 8(2), 01-06.

Kirkham MN, Cooper C, Broberg E, Robertson P, Clarke D, Pickett BE, Bikman BT, Reynolds PR, and Arroyo JA. 2024. Different lengths of gestational exposure to secondhand smoke or e-cigarette vapor induce the development of placental disease symptoms. Cells 2024, 13,1009.

Cayabyab KB, Shin MJ, Heimuli MS, Kim IJ, D’Agostino DP, Johnson RJ, Koutnik AP, Bellissimo N, Diamond DM, Norwitz NG, Arroyo JA, Reynolds PR, and Bikman BT. 2024. The metabolic and endocrine effects of a 12-week allulose-rich diet. Nutrients, 2024, 16, 1821.

Clarke DM, Curtis KL, Harward K, Scott J, Stapley BM, Kirkham MA, Clark ET, Robertson P, Chambers E, Warren CE, Bikman BT, Arroyo JA, and Reynolds PR. 2024. Embryonic mice with lung-specific RAGE up-regulation have enhanced mitochondrial respiration. J Respir, 2024, 4, 140-151.

Curtis KL, Chang A, Van Slooten R, Cooper C, Kirkham M, Armond T, deBernardi Z, Pickett BE, Arroyo JA, and Reynolds PR. 2024. Availability of receptors for advanced glycation endproducts (RAGE) influences differential transcriptome expression in lungs from mice exposed to chronic secondhand smoke (SHS). Int J Mol Sci., 2024; 25, 4940.

Warren CE, Campbell KM, Kirkham MN, Saito ER, Shin MJ, Remund NP, Cayabyab KB, Lim IJ, Heimuli MS, Reynolds PR, Arroyo JA, and Bikman BT. 2024. The effect of diesel exhaust particles on adipose tissue mitochondrial function and inflammatory status. Int J Mol Sci., 2024; 25, 4322.

Curtis KL, Hirschi KM, Tsai K, Clark ET, Stapley BM, Bikman BT, Reynolds PR, and Arroyo JA. 2024. Postnatal effects of antenatal secondhand smoke (SHS) exposure and the receptor for advanced glycation end-products (RAGE). Reprod Med., 5, 1-11.

Robin H, Trudeau C, Robbins A, Chung E, Rahman E, Gangmark-Strickland O, Licari FW, Winden DR, Orr DL, Arroyo JA, and Reynolds PR. 2024. A potential role for receptors for advanced glycation end-products (RAGE) in the development of secondhand smoke induced chronic sinusitis. Curr. Issues Mol. Biol, 46(1), 729-740.

Beard JD, Collingwood SC, LeCheminant JD, Peterson NE, Reynolds PR, Arroyo JA, South AJ, Farnsworth CB, Fong G, Heath T, Taylor M, Sanjel S, and Johnston JD. 2024. Personal breathing zone respirable dust and crystalline silica concentrations among workers at a brick kiln in Bhaktapur, Nepal. JOEH, 21:4, 247-258.

Johnston JD, Collingwood SC, LeCheminant JD, Peterson NE, Reynolds PR, Arroyo JA, South AJ, Farnsworth CB, Chartier RT, Layton LN, Hu JH, Penrod MS, Sanjel S, and Beard JD. 2023. Personal exposure to fine particulate air pollution among brick workers in Nepal. Atmosphere, 14, 1783.

Curtis KL, Homer KW, Wendt RA, Stapley BM, Clark ET, Harward K, Chang A, Clarke DM, Arroyo JA and Reynolds PR. 2023. Inflammatory cytokine elaboration following secondhand smoke (SHS) exposure is mediated in part by RAGE signaling. Int J Mol Sci., 24(21), 15645.

Walton CM, Saito E, Warren CE, Larsen JG, Remund NP, Reynolds PR, Hansen JM, and Bikman BT. 2023. Yerba maté (Ilex paraguariensis) supplement exerts beneficial, tissue specific effects on mitochondrial efficiency and redox status in healthy adult mice. Nutrients, 15, 4454.

Clarke DM, Curtis KL, Wendt RA, Stapley BM, Clark ET, Beckett N, Campbell KM, Arroyo JA and Reynolds PR. 2023. Decreased expression of pulmonary homeobox NKX2.1 and surfactant protein C in developing lungs that over-express receptors for advanced glycation end-products (RAGE). J. Dev. Biol. 11,33.

Norton C Clarke D, Holmstrom J, Stirland I, Reynolds PR, Jenkins TG, and Arroyo JA 2023. Altered Placental Epigenetic Profiles in Preeclamptic and Intrauterine Growth Restricted Patients. Cells, 12(8):1130.

Robin HP, Trudeau CN, Robbins AJ, Chung EJ, Rahman E, Gangmark-Strickland OL, Jordan S, Licari FW, Winden DR, Reynolds PR, and Arroyo JA. 2022. Inflammation and invasion in oral squamous cell carcinoma (OSCC) cells exposed to electronic cigarette vapor extract. Front Oncol, 12:917862.

Curtis KL, Clarke D, Hanegan M, Stapley B, Wendt R, Beckett N, Litchfield C, Campbell K, Reynolds PR, and Arroyo JA. 2022. Lung inflammation is associated with preeclampsia (PE) development in the rat. Cells, 11, 1884.

Hirschi KM, Tsai KYF, Curtis KL, Davis GS, Theurer BK, Kruyer AMM, Homer KW, Chang A, Van Ry PM, Arroyo JA, and Reynolds PR. 2022. RAGE signaling during tobacco smoke induced lung inflammation and potential therapeutic utility of SAGEs. BMC Pulm Med, 22(1):160.

Tsai KYF, Tullis B, Breithaupt KL, Fowers R, Jones N, Grajeda S, Reynolds PR, and Arroyo JA. 2021. A role for RAGE in DNA double strand breaks (DSBs) detected in pathological placentas and trophoblast cells. Cells, 10, 857.

Tsai KYF, Bikman BT, Reynolds PR, and Arroyo JA. 2021. Differential expression of mTOR related molecules in the placenta from gestational diabetes mellitus (GDM), intrauterine growth restriction (IUGR) and preeclampsia patients. Repro Biol, 21(2):100503.

Rose BJ, Weyand JA, Liu B, Smith JF, Perez BR, Goodman MA, Eggett DL, Arroyo JA, Reynolds PR, and Kooyman DL. 2021. Exposure to second-hand cigarette smoke exacerbates the progression of osteoarthritis in a surgical induced murine model. Histology and Histopath 36(3): 347-53.

Tsai KYF, Tullis B, Mejia J, Reynolds PR, and Arroyo JA. 2020. Regulation of trophoblast cell invasion by Pyruvate Kinase isozyme M2 (PKM2). Placenta 103: 24-32.

Tsai KYF, Hirschi Budge KM, Lepre AP, Rhees MS, Ajdaharian J, Geiler J, Epperson DG, Astle KJ, Winden DR, Arroyo JA and Reynolds PR. 2020. Cell invasion, RAGE expression and inflammation in oral squamous cell carcinoma (CSCC) cells exposed to e-cigarette flavoring. Clin Exp Dent Res. 2020 Dec;6(6):618-625.

Hirschi KM, Tsai KYF, Davis T, Clark JC, Knowlton MN, Bikman BT, Reynolds PR, and Arroyo JA. 2020. Growth Arrest Specific Protein (Gas)-6/AXL Signaling Induces Preeclampsia (PE) in Rats. Biol Reprod. 102(1):81.

Gibbs JL, Dallon BW, Lewis JB, Walton CM, Arroyo JA, Reynolds PR, and Bikman BT. 2019. Diesel exhaust particle exposure compromises alveolar macrophage mitochondrial bioenergetics. Int. J. Mol. Sci., 20 (22): 5598; doi:10.3390.

Tsai KYF, Hirschi KM, Llavina S ,Davis T, Long M, Bennett A, Sitton B, Arroyo JA, and Reynolds PR. RAGE and AXL expression following secondhand smoke (SHS) exposure in mice. 2019. Exp Lung Res, 45:9-10, 297-309.

Mejia J, Hirschi K, Tsai KYF, Long M, Tullis B, Bitter EEK, Bikman BT, Reynolds PR and Arroyo JA. 2019. Differential placental ceramide levels during gestational diabetes mellitus (GDM). Reprod Biol Endocrinol 17(1):81.

Hirschi KM, Tsai KYF, Edwards MM, Hall P, Mejia JF, Reynolds PR, and Arroyo JA. 2019. The mTOR family of proteins and the regulation of trophoblast invasion by Gas6. J Cell Signal 4:2, DOI: 10.4172/2576-1471.1000203.

Poornejad N, Momtahan N, Salehi ASM,Scott D, Fronk C, Roeder BL, Reynolds PR, Bundy B, and Cook AD. 2018. Corrigendum: Efficient Decellularization of whole porcine kidneys improves reseeded cell behavior. Biomed Mater. doi: 10.1088/1748-605X/aadd22.

Hirschi KM, Chapman S, Hall P, Ostergar A, Winden DR, Reynolds PR, and Arroyo JA. Gas6 induces invasion and reduces inflammatory cytokines in oral squamous cell carcinoma cells. J Oral Pathol Med. 2018 Jun 1. doi: 10.1111/jop.12738.

Lewis JB, Bodine JS, Gassman JR, Munoz SA, Milner DC, Dunaway DM, Egbert KM,Monson TD, Broberg DS, Arroyo JA, and Reynolds PR. 2018. Transgenic up-regulation of Claudin-6 decreases fine diesel particulate matter (DPM)-induced pulmonary inflammation. Environ Sci and Poll, 25(18): 18179-88.

Lewis JB, Jimenez FR, Merrell BJ,Kimbler B, Arroyo JA, and Reynolds PR. 2018. The expression profile of Claudin family members in the developing mouse lung and expression alterations resulting from exposure to secondhand smoke (SHS). Exp Lung Res, 11:1-12. doi: 10.1080/01902148.2017.140984.

Chapman S, Mick M, Hall P,Mejia C, Sue S, Wase BA, Nguyen MA, Whisenant EC, Wilcox SH, Winden DR, Reynolds PR, and Arroyo JA. 2018. Cigarette smoke extract induces oral squamous cell carcinoma cell invasion in a receptor for advanced glycation end-product-dependent manner. Eur J Oral Sci, doi: 10.1111/eos.12395.

Lewis JB, Mejia C, Jordan C, Monson TD, Bodine JS, Dunaway TM, Egbert KM, Lewis AL, Wright TJ, Ogden KC, Broberg DS, Hall PD, Nelson SM, Hirschi KM, Reynolds PR and Arroyo JA. 2017. Inhibition of the receptor for advanced glycation end-products (RAGE) protects from secondhand smoke (SHS)-induced intrauterine growth restriction (IUGR) in mice. Cell Tissue Res, 2017 Sep 26. doi: 10.1007/s00441-017-2691-z.

Kumar V, Fleming T, Terjung S, Gorzelanny C, Gebhardt C, Agrawal R, Mall MA, Ranzinger J, Zeier M, Madhusudhan T, Ranjan S, Iserman B, Liesz A, Deshpande D, Häring HU, Biswas SK, Reynolds PR, Hammes HP, Peperkok R, Angel P, Herzig S and Nawroth PP. 2017. Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair. Nuc Acid Res, 2017 Aug 9. doi: 10.1093/nar/gkx705.

Poornejad N, Buckmiller E, Schaumann L, Wang H, Wisco J, Roeder B, Reynolds P, and Cook A. 2017. Re-epithelialization of whole porcine kidneys with renal epithelial cells. J Tissue Eng 8:1-22, DOI 10.1177/2041731417718809.

Taylor OJ, Thatcher MO, Carr ST, Gibbs J, Trumbull AM, Harrison ME, Winden DR, Pearson MJ, Tippetts TS, Holland WL, Reynolds PR, and Bikman BT. 2017. High-mobility Group Box 1 disrupts metabolic function with cigarette smoke exposure in a ceramide-dependent manner. Int J Mol Sci. 18(5):1099; doi: 10.3390/ijms18051099.

Napa K., Baeder AC, Witt JE, Rayburn ST, Miller MG, Dallon BW, Gibbs JL, Wilcox SH, Winden DR, Reynolds PR, and Bikman BT. 2017. LPS from P. Gingivalis negatively alters gingival cell mitochondrial bioenergetics. Int J Dentistry2017: 2697210.

Monson T,Wright T, Galan HL, Reynolds PR, and Arroyo JA. 2017. Caspase dependent and independent mechanisms of apoptosis across gestation in a sheep model of placenta insufficiency and intrauterine growth restriction. Apoptosis 22(5): 710-718.

Lewis JB, Hirschi KM, Arroyo JA, Bikman BT, Kooyman DT, and Reynolds PR. 2017. Plausible roles for RAGE in conditions exacerbated by direct and indirect (secondhand) smoke exposure. Int J Mol Sci. 18(3):652; doi:10.3390/ijms18030652.

Sanders NT, Dutson DJ, Durrant JW, Lewis JB, Wilcox SH, Winden DR, Arroyo JA, Bikman BT, and Reynolds PR. 2017. Cigarette Smoke Extract (CSE) Induces RAGE-Mediated Inflammation in the Ca-9-22 Gingival Carcinoma Epithelial Cell Line. Archives of Oral Biology80:95-100.

Black CS, Creapeau PK, Sheffiend ID, Macdonald JR, Wooton DJ, Maek M, Eggett DL, Reynolds PR, and Kooyman DL. 2017. Identification of the tidemark line of calcification in osteoarthritic cartilage using a stain for alkaline phosphatase. J Arthritis6:230. Doi:10.4172/2167-7921.1000230.
Jimenez FR, Lewis JB, Belgique ST, Milner DC, Lewis AL, Dunaway TM, Egbert KM, Winden DR, Arroyo JA, and Reynolds PR. 2016. Cigarette smoke and decreased oxygen tension inhibit pulmonary Claudin-6 expression. Exp Lung Res, 42(8-10):440-452.

Lewis JB, Milner DC, Lewis AL, Dunawy TM, Egbert KM, Albright SC, Merrell BJ, Monson TD, Broberg DS, Gassman JR, Thomas DB, Arroyo JA and Reynolds PR. 2016. Up-regulation of Claudin-6 in the distal lung impacts secondhand smoke-induced inflammation. Int J Environ Res Public Health, 13:1018; doi:10.3390/ijerph13101018.

Mejia C, Lewis J, Jordan C, Mejia J, Ogden C, Monson T, Winden D, Reynolds PR, and Arroyo JA. 2016. Decreased activation of placental mTOR family members is associated with the induction of intrauterine growth restriction (IUGR) by secondhand smoke (SHS) in the mouse. Cell Tissue Res, 9 Sept 2016, DOI: 10.1007/s00441-016-2496-5.

Poornejad N, Schaumann LB, Buckmiller EM, Momtahan N, Gassman JR, Ma HH, Roeder BL, Reynolds PR and Cook AD. The impact of decelluralization agents on renal tissue extracellular matrix. J Biomater Appl, 0885328216656099.

Chavez EM, Mecham DK, Black JW, Graf JW, Wilhelm SK, Anderson KM, Mitchell JA, Macdonald JR, Hollis WR, Eggett DL, Reynolds PR, and Kooyman DL. Malocclusion Model of Temporomandibular Joint Osteoarthritis in Mice with and Without Receptor For Advanced Glycation End Products. Archives of Oral Biology, 69:47-62.

Long E, Motwani R, Reece D, Pettit N, Hepworth J, Wong P, Reynolds PR, and Seegmiller RE. 2016. The role of TGF-b1 in osteoarthritis of the temporomandibular joint in two genetic mouse models. Arch Oral Biol 67:68-73.

Poornejad N, Momtahan N, Salehi ASM, Scott D, Fronk C, Roeder BL, Reynolds PR, Bundy B, and Cook AD. 2016. Efficient decellularization of whole procine kidneys improves reseeded behavior. Biomed Materials 11(2):025003.

Baeder AC, Napa K, Richardson ST, Taylor OJ, Anderson SG, Wilcox SH, Winden DR, Reynolds PR, and Bikman BT. 2016. Oral Gingival Cell Cigarette Smoke Exposure Induces Muscle Cell Metabolic Disruption. Int J Dentistry 2016: 2763160.

Alexander KL, Mejia CA, Jordan C, Nelson MB, Howell BM, Jones CM, Reynolds PR, and Arroyo JA. 2015. Differential Receptor for Advanced Glycation End-Products (RAGE) Expression in Preeclamptic, Intrauterine Growth Restricted, and Gestational Diabetic Placentas. Am J Reprod Immunol, 75(2):172-180.

Kimball R, Wayment M, Merrill D, Wahlquist T, Reynolds PR, and Arroyo JA. 2015. Hypoxia reduces placental mTOR activation in a hypoxia-induced model of intrauterine growth restriction (IUGR). Physiol Rep 3(12):e12651.

Poornejad N, Nielson J, Morris R, Gassman J, Reynolds PR, Roeder BL, and Cook AD. 2015. Comparison of four decontamination treatments on porcine renal dECM structure, composition, and support of human rena; cortical tubular epithelium cells. J Biomater Appl, doi:10.1177/0885328215615760.

Siebert M, Wilhelm SK, Kartchner JZ, Mecham D, Reynolds PR, and Kooyman DL. 2015. Effect of pharmacological blocking of TLR4 on osteoarthritis in mice. J Arthritis: 164. Doi:10.4172/2167-7921.1000164.

Olsen DS, Goar WA, Nichols BA, Bailey KT, Christensen SL, Merriam KR, Reynolds PR, Wilson E, Weber KS, and Bridgewater LC. 2015. Targeted mutation of nuclear bone morphogenetic protein 2 (nBMPR2) impairs secondary immune response in a mouse model. BioMed Res Int, vol. 2015, Article ID 975789. doi:10.1155/2015/975789.

Momtahan N, Poornejad N, Struk JA, Castleton AA, Herrod BJ, Vance BR, Eatough JP, Roeder BL, Reynolds PR, and Cook AD. 2015. Automation of pressure control improves whole porcine heart decellularization. T Tissue Engineering C, DOI: 10.1089/ten.tec.2014.0709.

Jimenez FR, Belgique ST, Lewis JB, Albright SA, Jones CM, Howell BM, Mika AP, Jergensen TR, Gassman JR, Morris RJ, Arroyo JA, and Reynolds PR. 2015. Conditional pulmonary over-expression of Claudin-6 (Cldn6) during embryogenesis delays lung morphogenesis. Int J Dev Biol, doi: 10.1387/ijdb.150086pr.

Nelson MB, Swensen AC, Winden DR, Bodine JS, Bikman BT, and Reynolds PR. 2015. Cardiomyocyte mitochondrial respiration is reduced by receptor for advanced glycation end-products (RAGE) signaling in a ceramide-dependent manner. AJP: Heart and Circulation Physiology 309:H63-H69.

Poornejad N, Frost TS, Scott DR, Elton BB, Reynolds PR, Roeder BL, and Cook AD. 2015. Freezing/thawing without cryoprotectant damages native but not decellularized porcine renal tissue. Organogenesis in press.

Tippetts TS, Winden DR, Swensen AC, Nelson MB, Thatcher MO, Saito RR, Condie TB, Simmons KJ, Judd AM, Reynolds PR, Bikman BT. 2014. Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. BMC Cardiovasc Disord., 2014 Nov 22; 14:165.

Bodine BG, Bennion BG, Leatham E, Jimenez FR, Wright AJ, Jergensen ZR, Erickson CJ, Jones CM, Johnson JP, Knapp SM, and Reynolds PR 2014. Conditionally induced RAGE expression by proximal airway epithelial cells in transgenic mice causes lung inflammation. Respir Res, 15(1):133.

Winden DR, Barton DB, Betteridge BC, Bodine JS, Jones CM, Rogers GD, Chavarria M, Wright AJ, Jergensen ZR, Jimenez FR, and Reynolds PR 2014. Antenatal exposure of maternal secondhand smoke (SHS) increases fetal lung expression of RAGE and induces RAGE-mediated pulmonary inflammation. Respir Res, 15(1):129.

Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Anderson MC, Johnson IE, Porter JP, Prince JT, Reynolds PR, Bikman BT. 2014. Ceramides mediate cigarette smoke-induced metabolic disruption in mice. Am J Physiol Endocrinol Metab., 2014 Sep 30, Epub ahead of print.

Wood TT, Winden DR, Marlor DR, Wright AJ, Jones CM, Chavarria M, Rogers GD, Reynolds PR. 2014. Acute Secondhand Smoke-Induced Pulmonary Inflammation is Diminished in RAGE Knock out Mice. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 26. Epub ahead of print.

Jimenez F.R., Lewis B.L., Belgique S.T., Wood T.T., and Reynolds P.R. 2014. Developmental lung expression and transcriptional regulation of Claudin-6 by TTF-1, Gata-6, and FoxA2. Respir Res, 15(1):70.

Barton D.B., Betteridge B.C., Earley T.D., Curtis C.S., Robinson A.B., and Reynolds P.R. 2014. Primary alveolar macrophages exposed to diesel particulate matter increase RAGE expression and activate RAGE signaling. Cell Tissue Res, 25 May 2014, Epub ahead of print.

Winden D.R., Ferguson N.T., Bukey B.R., Geyer A.J., Wright A.J., Jergensen Z.R., Robinson A.B., Stogsdill J.R., and Reynolds P.R. 2013. Conditional over-expression of RAGE by embryonic alveolar epithelium compromises the respiratory membrane and impairs endothelial cell differentiation. Respir Res 14(1):108.

Larkin D.J, Kartchner J.Z., Doxey A.S., Hollis W.R., Rees J.L., Wilhelm S.K., Draper C.S., Peterson D.M., Jackson G.G., Ingersoll C., Haynie S.S., Chavez E., Reynolds P.R., Kooyman D.L. 2013. Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-Products (RAGE). Frontiers in Integ Physiol 4: 121. doi: 10.3389/fphys.2013.00121.

Stogsdill M.P., Stogsdill J.A., Bodine B.G., Fredrickson A.C., Sefcik T.L., Wood T.A., Kasteler S.K., and Reynolds P.R. 2013. Conditional RAGE over expression in the adult murine lung causes airspace enlargement and induces inflammation. Am J Resp Cell Mol Biol 49(1):128-134.

Ricks M.L., Farrell J.T., Falk D.J., Holt D.W., Rees M., Carr J., Williams T., Nichols B.A., Bridgewater L.C., Reynolds P.R., Kooyman D.L., and Seegmiller R.E. 2013. Osteoarthritis in temporomandibular joint of Col2a1 mutant mice. Advances in Oral Biology 58(9):1092-9.

Robinson A.B., Stogsdill J.A., Lewis J.P., Wood T.A., and Reynolds P.R. 2012. RAGE and tobacco smoke: Insights into modeling Chronic Obstructive Pulmonary Disease. Frontiers in Resp Physiol 3:301. doi: 10.3389/fphys.2012.00301.

Robinson A.B., Dickson, K.D., Bennion B.G., and Reynolds P.R. 2012. RAGE signaling by alveolar macrophages influences tobacco smoke-induced inflammation. AJP: Lung Cell Mol Physiol 302(11):L1192-9.

Stogsdill J.A., Stogsdill M.P., Porter J.L., Hancock J.M., Robinson A.B., and Reynolds P.R. 2011. Embryonic over-expression of RAGE by alveolar epithelium induces an imbalance between proliferation and apoptosis. Am J Resp Cell Mol Biol. 47(1):60-6.

Reynolds P.R., Stogsdill J.A., Stogsdill M.P., and Heimann N.B. 2011. Up-Regulation of RAGE by Alveolar Epithelium Influences Cytodifferentiation and Causes Severe Lung Hypoplasia. Am J Resp Cell Mol Biol 45(6): 1195-202.

Bukey B.R., Geyer A.J., and Porter J.L. and Reynolds P.R. 2011. Immunohistochemical detection and regulation of alpha 5 nicotinic acetylcholine receptor (nAChR) subunits by FoxA2 during mouse lung organogenesis. Respir Res 12(1):82.

Reynolds P.R., Allison C.H., and Willnauer C.P. 2010. TTF-1 Regulates Alpha 5 Nicotinic Acetylcholine Receptor (nAChR) Subunits in Proximal and Distal Lung Epithelium. Respir Res 11:175.

Reynolds P.R., Wasley K.M., and Allison C.H. 2010. Diesel Particulate Matter Induces RAGE Expression in Pulmonary Epithelium and RAGE Signaling Influences NF-kB-Mediated Inflammation. Environ Health Per 119(3):332-9.

Reynolds P.R., Kasteler S.D., Schmitt R.E. and Hoidal J.R. 2010. RAGE Signals Through Ras During Tobacco Smoke-Induced Pulmonary Inflammation. Am J Resp Cell Mol Biol 45(2):411-8.

Rao N.V., Argyle B., Xu Z., Reynolds P.R., Walenga J.M., Prechel M., Prestwich G.D., Hoidal J.R., and Kennedy T.P. 2010. Low Anticoagulant Heparin Targets Multiple Sites in Inflammation, Suppresses Heparin-Induced Thrombocytopenia and Inhibits Interaction of RAGE with its Disparate Ligands. Am J Physiol Cell Physiol 299(1):C97-110.

Reynolds P.R., Kasteler S.D., Sturrock A., Sanders K. Kennedy T.P. and Hoidal J.R. 2009. RAGE Targeting Protects Against Hyperoxia-Induced Lung Injury in Mice. Am J Resp Cell Mol Biol 42(5):545-51.

Reynolds P.R., Kasteller S., Cosio M.G., Sturrock A., Huecksteadt T.P. and Hoidal J.R. 2008. RAGE: Developmental Expression and Positive Feedback Regulation by Egr-1 During Cigarette Smoke Exposure in Pulmonary Epithelial Cells. AJP: Lung Cell Mol Physiol 294(6):L1094-101.

Reynolds P.R. and J.R. Hoidal. 2006. Cigarette Smoke-Induced Egr-1 Upregulates Pro-Inflammatory Cytokines in Pulmonary Epithelial Cells. Am J Resp Cell Mol Biol 35(3):314-9.

Reynolds P.R. and J.R. Hoidal. 2005. Temporal-Spatial Expression and Transcriptional Regulation of a₇ Nicotinic Acetylcholine Receptor (nAChR) by TTF-1 and Egr-1 During Murine Lung Development. J Biol Chem. 280(37):32548-54.

Mukherjee T.P., Reynolds P.R and Hoidal J.R. 2005. Differential Effect of Estrogen Receptor Alpha and Beta Agonists on the Receptor for Advanced Glycation End Product Expression in Human Microvascular Endothelial Cells. Biochim Biophys Acta 1745(3):300-9.

Reynolds P.R., M.L. Mucenski, T.D. LeCras, W. C. Nichols and J.A. Whitsett. 2004. Midkine (MK) induces myocardin during hypoxia and causes pulmonary vascular remodeling. J Biol. Chem. 279(35):37124-32.

Reynolds P.R., M.L. Mucenski, and J.A. Whitsett. 2003. Thyroid Transcription Factor (TTF)-1 Regulates the expression of Midkine (MK) During Lung Morphogenesis. Dev. Dyn. 227:227-237.

Reynolds P.R., G.B. Schaalje, and R.E. Seegmiller. 2003. Combination Therapy with Folic Acid and Methionine in the Prevention of Retinoic Acid-Induced Cleft Palate in Mice. BDRA 67:168-173.