Research Description: I research the influenza A/M2 protein, which is a key target in blocking viral replication. Specifically, I use electrophysiology techniques (two-electrode voltage-clamp) to measure the proton current blocked by novel organometallic compounds developed by our research group. As well, I use molecular dynamics, quantum mechanics, and quantum mechanic/molecular mechanic hybrid simulations to show the mechanism of block by the organometallic compounds.
