Publications

Jacob F. Smith, Evan G. Starr, Michael A. Goodman, Romney B. Hanson, Trent A. Palmer, Jonathan B. Woolstenhulme, Jeffery A. Weyand, Andrew D. Marchant, Shawen L. Christensen, Tanner K. Nelson, Matthew Sterling, Brandon J. Rose, James P. Porter, Dennis L. Eggett and David L. Kooyman. TopicalApplication of Wogonin Provides a Novel Treatment of Knee Osteoarthritis. 2020. Frontiers in Physiology - Clinical and Translational Physiology. 11 (article 80): 1-9

Sheffield ID, McGee MA, Glenn SJ, Baek DY, Coleman JM, Dorius BK, Williams C, Rose BJ, Sanchez AE, Goodman MA, et al. 2018. Osteoarthritis-Like Changes in Bardet–Biedl Syndrome Mutant Ciliopathy Mice (Bbs1M390R=M390R): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation.. Frontiers in Physiology. doi:https://doi.org/10.3389/fphys.2018.00708

Black CS, Creapeau PK, Sheffiend ID, MacDonald JR, Wooton DJ, Maek M, Eggett DL, Reynolds PR, Kooyman DL. 2017. Identification of the tidemark line of calcification in osteoarthritic cartilage using a stain for alkaline phosphatase. J Arthritis. 6:230. doi:10.4172/2167-7921.1000230

Lewis JB, Hirschi KM, Arroyo JA, Bikman BT, Kooyman DL, Reynolds PR. 2017. Plausible Roles for RAGE in Conditions Exacerbated by Direct and Indirect (Secondhand) Smoke Exposure. Int J Mol Sci. 18(3):E652. doi:10.3390/ijms18030652

Kooyman DL, Rose BJ. 2016. A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology. Disease Markers. 7 pages. doi:4895050

Chavez EM, Mecham DK, Black CS, Graf JW, Steel SD, Wilhelm SK, Andersen KM, Mitchell JA, Macdonald JR, Hollis WR, et al. 2016. Malocclusion Model of Temporomandibular Joint Osteoarthritis in Mice With and Without Receptor for Advanced Glycation End Products.. Archives of Oral Biology. 69:47-62.

Siebert M, Wilhelm SK, Kartchner JZ, Mecham D, Reynolds PR, Kooyman DL. 2015. Effect of Pharmacological Blocking of TLR-4 on Osteoarthritis in Mice. Journal of Arthritis. 4(3). doi:http://dx.doi.org/10.4172/2167-7921.1000164

Macdonald DW, Squires RS, Avery S, Adams J, Baer M, Cunningham CR, Heimann N, Kooyman DL, Seegmiller RE. 2013. Structural Variations in Articular Cartilage Matrix Are Associated with Early-Onset Osteoarthritis in the Spondyloepiphyseal Dysplasia Congenita (Sedc) Mouse. International Journal of Molecular Science. 14:16515-16531.

Ricks ML, Farrell JT, Falk DJ, Holt DW, Rees M, Carr J, Williams T, Nichols BA, Bridgewater LC, Reynolds PR, et al. 2013. Osteoarthritis in Temporomandibular Joint of Col2a1 Mutant Mice. Archives of Oral Biology. 58(9):1092-9.

Larkin DJ, Kartchner JZ, Doxey AS, Hollis WR, Rees JL, Wilhelm SK, Draper CS, Peterson DM, Jackson GG, Ingersoll C, et al. 2013. Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-products (RAGE). Frontiers in Physiology. 4:121-128.

Kooyman DL, Airmet K, Hinckley JD, Tree LT, Moss M, Blumell S, Ulicny K, Gustafson AK, Weed M, Theodosis R, et al. 2012. Construction of a Llama Bacterial Artificial Chromosome Library. Journal of Biomedicine and Biotechnology. 2012(Article ID 371414):4.

Holt DW, Henderson ML, Stockdale CE, Farrell JT, Kooyman DL, Bridgewater LC, Seegmiller RE. 2012. Osteoarthritis-like changes in the heterozygous sedc mouse associated with the HtrA1-Ddr2-Mmp-13 degradative pathway: A new model of osteoarthritis.. Osteoarthritis and Cartilage. 20:430-439.

Holt DW, Henderson ML, Stockdale CE, Ferrell JT, Kooyman DL, Bridgewater LC, Seegmiller RE. 2012. Osteoarthritis-like changes in the heterozygous sedc mouse associated with the HtrA1-Ddr2-Mmp-13 degradative pathway: a new model of osteoarthritis.. Ostoeoarthritis and Cartilage. 20:430-439.

Thomson DM, Hancock CR, Evanson BG, Kenney SG, Mallan BB, Mongillo AD, Brown JD, Hepworth S, Fillmore N, Parcell AC, et al. 2010. Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice. J Appl Physiol. 108:1775-1785.

Abstracts

Rose BJ, Behrens N, Harris S, Maloy S, Nelson T, Smith JF, Starr E, Woolstenhulme J, Watt RK, Kooyman DL. 2019. Expression of Iron Regulatory Proteins in Healthy and Osteoarthritic Chondrocytes. FASEB Journal. 33(1):487.18.

Smith JF, Starr EG, Goodman MA, Hanson RB, Palmer TA, Woolstenhulme JB, Weyand JA, Sterling MT, Marchant AD, Rose BJ, et al. 2019. Topical Application of Wogonin Provides a Novel Treatment of Knee Osteoarthritis. FASEB Journal. 33(1):487.22.

Liu B, Rose BJ, Weyand JA, Perez BR, Clark C, Hirschi K, Arroyo JA, Reynolds PR, Kooyman DL. 2018. Exposure to second-hand cigarette smoke exacerbates the progression of OA.. Osteoarthritis and Cartilage. 26(S126):S126.

Rose BJ, Goodman MA, Kooyman DL. 2018. Intraperitoneal myriocin upregulates transforming growth factor 1 (tgf-1) expression in murine destabilization of the medial meniscus model of osteoarthritis—evidence for a role of ceramide species in cartilage homeostasis.. FASEB. 32(1):LB579.

Glenn SJ, Williams C, Daines J, Jensen A, Starley J, Suli A, Kooyman DL. 2017. Zebrafish as a structural model for studying osteoarthritis. Osteoarthritis and Cartilage. 25:S76.

Black CS, Crepeau PK, Sheffield ID, Macdonald JR, Wootton DJ, Baek M, Eggett DL, Reynolds PR, Kooyman DL. 2015. Identification of the Tidemark Line of Calcification in Osteoarthritic Cartilage Using a Stain for Alkaline Phosphatase.. Osteoarthritis and Cartilage. 23(Supplement 2):28.

Kooyman DL, Reynolds PR, Wilhelm SK, Mecham D, Chavez EM, Kartchner JZ, Crepeau P, Andersen K, Vandruff J, Robinson M, et al. 2014. Blocking the receptor for advanced glycation end-products but not Toll-like receptor 4 attenuates the progression of OA. FASEB J. 28:835.13.

Kooyman DL, Chavez EM, Mecham D, Wilhelm SK, Black CS, Mitchell J, Andersen K, Graf J, Macdonald J. 2014. Knocking out RAGE disrupts natural repair of condylar cartilage during osteoarthritis. FASEB J. 28:835.14.

Kooyman DL, Andersen K, Black CS, Crepeau P, Kartchner JZ, Mecham D, Robinson M, Wilhelm SK, Chavez EM. 2014. TGF-β1 and HtrA1 interactive pathway in the molecular progression of osteoarthritis. FASEB J. 28:1139.9

Kooyman DL, Seegmiller RE, Wong P, Reece D, Hepworth J, Wilhelm SK, Mecham D. 2014. The role of TGFβ1 and HTRA1 in the pathogenesis of TMJ osteoarthritis. FASEB J. 28:922.8

Kooyman DL, Kartchner JZ, Peterson DM, Larkin DJ, Doxey AS, Hollis WR, Rees JL, Jackson GG, Wilhelm SK, Haynie SS, et al. 2013. The temporal expression of biomarkers associated with osteoarthritis after knee destabilizing surgery in mice with and without Receptor for Advanced Glycation End Products (RAGE). FASEB Journal. LB139.

Wilhelm SK, Doxey AS, Kartchner JZ, Vandruff J, Andersen K, Draper CS, Chavez E, Reynolds PR, Kooyman DL. 2013. Apoptosis Associated with Osteoarthritis is Attenuated in Mice Lacking the Receptor for Advanced Glycation End Products (RAGE). FASEB Journal. 27:573.5

Larkin DJ, Kartchner JZ, Doxey AS, Hollis WR, Rees JL, Wilhelm SK, Draper CS, Peterson DM, Jackson GC, Ingersoll C, et al. 2013. Inflammatory markers associated with osteoarthritis after destabilization surgery in mice with and without Receptor for Advanced Glycation End Products (RAGE). FASEB Journal. 27:573.3

Kooyman DL, Ricks ML, Falk DJ, Farrell J, Rees MB, Carr JM, Williams DT, Bridgewater LC, Seegmiller RE. 2012. Premature osteoarthritis in the temporomandibular joint of heterozygous disproportionate micromelia mice. Experimental Biology. 26:LB 115.

Presentations

Glenn SJ, Williams C, Daines J, Jensen A, Starley J, Suli A, Kooyman DL. Zebrafish as a structural model for studying osteoarthritis. Osteoarthritis Society International Congress. Las Vegas, NV. 2017 .

Sheffield ID, Nelson MA, Baek M, Coleman JM, Glenn S, Dorius B, Sanchez AE, Williams C, Rose BJ, Sheffield VC, et al. The role of chondrocyte primary cilia in osteoarthritis. Osteoarthritis Society International Meeting. Brussels, Belgium. 2016 .

Andersen K, Black CS, Crepeau P, Kartchner JZ, Mecham D, Robinson M, Wilhelm SK, Chavez EM, Kooyman DL. TGF-β1 and HtrA1 interactive pathway in the molecular progression of osteoarthritis. Federation of American Societies for Experimental Biology. San Diego, CA. 2014 .

Wong P, Reece D, Hepworth J, Wilhelm SK, Mecham D, Kooyman DL, Seegmiller RE. The role of TGFβ1 and HTRA1 in the pathogenesis of TMJ osteoarthritis. Federation of American Societies for Experimental Biology. San Diego, CA. 2014 .

Grose JH, Kooyman DL, Anderson J, Buckley A, Pezoa Cabeza Y, Emery H, Fullwood R, Hecht K, Jackson K, Jones E, et al. E. colin: A two circuit system for colin cancer detection. IGEM Regional Jamboree. Standford University. 2012 .

Ricks M, Falk DJ, Farrell JT, Rees MB, Carr JM, Williams DT, Kooyman DL, Bridgewater LC, Seegmiller RE. Premature osteoarthritis in the temporomandibular joint of heterozygous disproportionate micromelia mice. American Society for Biochemistry and Molecular Biology Annual Meeting. San Diego, California. 2012 .

Grose JH, Kooyman DL, Biggs M, Chamberlain C, Merrill M, Sabin D, Sabin M, Roberts J, Williams L, Alley A, et al. E. colinoscopy. Current topics in Chemistry. BYU. 2011 .

Grose JH, Kooyman DL, Biggs M, Chamberlain C, Merrill M, Sabin D, Sabin M, Roberts J, Williams L, Alley A, et al. Evolving a thermoswitch sensitive to narrow temperature shifts. IBE Western Regional Student Conference. Utah State University. 2011 .

Grose JH, Kooyman DL, Biggs M, Chamberlain C, Merrill M, Sabin D, Sabin M, Roberts J, Williams L, Alley A, et al. E. colinoscopy. IGEM Worldchampionship Jamboree. MIT. 2011 .

Grose JH, Kooyman DL, Biggs M, Chamberlain C, Merrill M, Sabin D, Sabin M, Roberts J, Williams L, Alley A, et al. E. colinoscopy. IGEM Regional Jamboree. Indianapolis. 2011 .

Thomson DM, Hancock CR, Evanson BG, Kenney SG, Malan BB, Mongillo AD, Brown JD, Hepworth S, Fillmore N, Parcell AC, et al. Muscle-specific LKB1 knockout leads to skeletal muscle dysfunction. FASEB Summer Research Conference- AMPK:Central Regulatory System in Metacolism & Growth. Kyoto, Japan. 2010 .