Jared Barrott

Research Interests

Personalized medicine in oncology relies on extracting molecular information from the tumor to understand the vulnerabilities that attacked with targeted therapies. Sarcomas are a rare classification of cancer that is understudied and has limited targeted therapy options. In the Barrott lab, we create models of bone and muscle cancers to test novel therapies. We use traditional cancer cell lines as well as innovative patient-derived 3D tumor organoid models to test anti-cancer therapies. Once therapies have shown promise in these models, we advance the most promising candidates to test in genetically engineered mouse models where we can assess safety and efficacy before going into people. One class of anti-cancer therapy that we are particularly interested in is antibody-drug conjugates. Using antibodies as a homing beacon, we can deliver precise therapies that target unique antigens expressed on the cancers.

Teaching Interests

I teach introductory cell biology courses and provide experiential opportunities for graduate and undergraduate students in the lab. I look forward to teaching more advanced cancer biology classes in the future. In my previous academic appointment, I taught genetics and pharmacogenomics in a pharmacy program to help students better understand how genetics influence how patients respond to drugs.

Honors and Awards

• Silver Medal, International Genetic Engineering Machine Competition (2024 - 2024)
• Faculty of the Month, Rho Chi Students at Idaho State University (2023 - 2023)

Memberships

• Association of Molecular Pathology (2023 - Present)
• Biohive (2023 - Present)
• Society for Functional Precision Medicine (2019 - Present)
• Connective Tissue Oncology Society (2015 - Present)
• American Association for Cancer Research (2014 - Present)

Professional Citizenship

• Grant Proposal Reviewer, External, NIH (2025 - 2025)
• Grant Proposal Reviewer, External, University of Arizona (2024 - 2025)
• Reviewer, Ad Hoc Reviewer, Journal of Bone Oncology (2024 - 2024)
• Grant Proposal Reviewer, External, NIH (2024 - 2024)
• Guest Speaker, Society for Functional Precision Medicine (2024 - 2024)
• Grant Proposal Reviewer, External, NIH (2023 - 2023)

Courses Taught

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Publications

Kaniz Fatema Yangliang Wang Adriene Pavek Zachary Larson Christopher Nartker Shawn Plyler Amanda Jeppson Breanna Mehling Mario Capecchi Kevin Jones Jared James Barrott Jeffrey Okojie Nicole O'Neal Mackenzie Burr Peyton Worley Isaac Packer DeLaney Anderson Jack Davis Bridger Kearns Kaniz Fatema Ken Dixon Jared James Barrott Amir Pozner Shiv P Verma Li Li Shuxin Wang Jared Barrott M L Nelson Jamie Yu G L Negri S Colborne C S Hughes J F Zhu S L Lambert L S Carroll K Smith-Fry M G Stewart Sarmishta Kannan Brodie Jensen K L Mortenson C John S Sikdar H Liu N H Dang J Bourdage J Li J M Vahrenkamp J S Groundland R Wustrack D L Senger F J Zemp D J Mahoney J Gertz X Zhang A J Lazar M Hirst G B Morin T O Nielsen P S Shen Kevin B Jones Benjamin B Ozenberger Li Li Emily R Wilson Alexander J Lazar Jared Barrott Kevin B Jones Jeffrey Okojie Sarah McCollum Jared Barrott Farjana Afrin Sameena Mateen Jordan Oman James Lai Jared Barrott Srinath Pashikanti Sana Khajeh Pour Sameena Mateen Srinath Pashikanti Jared Barrott Ali Aghazadeh-Habashi Kaniz Fatema Zachary Larson Jared Barrott Sarah McCollum Austin Kalivas Matt Kirkham Kaden Kunz Jeffrey Okojie Adriene Pavek Jared Barrott Cynthia A Blanton Jared Barrott Kaden Kunz Ella Bunde H M Streff C A Sparks D W Williams A M Gabaldόn Kaniz Fatema Jared Barrott J Li T S Mulvihill L Li Jared James Barrott M L Nelson L Wagner I C Lock A Pozner S L Lambert B B Ozenberger M B Ward A H Grossmann T Liu A Banito B R Cairns K B Jones E Panza B B Ozenberger K M Straessler Jared James Barrott L Li Y Wang M Xie A Boulet S W Titen C C Mason A J Lazar L Ding M R Capecchi K B Jones A Pavek C Nartker M Saleh M Kirkham S Khajeh Pour A Aghazadeh-Habashi Jared James Barrott J Stegelmeier C Nartker C Barnes H Rayo R Hoover J Boyle S O'Connor Jared James Barrott M Kirkham A Kalivas K Fatema S Luelling B H Dubansky B Dubansky K B Jones Jared James Barrott S Pashikanti F Afrin T C Meldrum J L Stegelmeier A Pavek Y A Habashi K Fatema Jared James Barrott A Mika S E Luelling A Pavek C Nartker A L Heyneman K B Jones Jared James Barrott J W Potter K B Jones Jared James Barrott Jared James Barrott B E Illum H Jin M L Hedberg Y Wang A Grossmann M Haldar M R Capecchi K B Jones A N Laporte N M Poulin Jared James Barrott X Q Wang A Lorzadeh R Vander Werff K B Jones T M Underhill T O Nielsen H Jin Jared James Barrott M G Cable M J Monument D M Lerman K Smith-Fry D Nollner K B Jones Jared James Barrott J F Zhu K Smith-Fry A M Susko D Nollner L D Burrell A Pozner M R Capecchi J T Yap L A Cannon-Albright X Deng K B Jones A N Laporte Jared James Barrott R J Yao N M Poulin B A Brodin K B Jones T M Underhill T O Nielsen Jared James Barrott L A Kafchinski H Jin J W Potter S D Kannan R Kennedy T Mosbruger W L Wang J W Tsai D M Araujo T Liu M R Capecchi A J Lazar K B Jones L Horne F R Avilucea H Jin Jared James Barrott K Smith-Fry Y Wang B H Hoang K B Jones K B Jones Jared James Barrott M Xie M Haldar H Jin J F Zhu M J Monument T L Mosbruger E M Langer R L Randall R K Wilson B R Cairns L Ding M R Capecchi Jared James Barrott B E Illum H Jin J F Zhu T Mosbruger M J Monument K Smith-Fry M G Cable Y Wang A H Grossmann M R Capecchi K B Jones Jared James Barrott P F Hughes T Osada X Y Yang Z C Hartman D R Loiselle N L Spector L Neckers N Rajaram F Hu N Ramanujam G Vaidyanathan M R Zalutsky H K Lyerly T A Haystead Jared James Barrott T A Haystead P F Hughes Jared James Barrott D A Carlson D R Loiselle B L Speer K Bodoor L A Rund T A Haystead Jared James Barrott G M Cash Aaron Jeffrey Smith Jeffery Richard Barrow L C Murtaugh

Presentations